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Research reviews

How fasting strategies compare with continuous restriction

Intermittent fasting strategies and their effects on body weight and other cardiometabolic risk factors: systematic review and network meta-analysis of randomised clinical trials

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Fasting Free source summary: https://fastingfree.com/education/semnani-azad-2025-review/

PLAIN-LANGUAGE SUMMARY

What it found

Benefits were broadly similar to continuous restriction. Alternate-day fasting showed a small additional weight difference, concentrated in shorter trials.

Keep these limits in view

Protocols and populations varied. Network comparisons include indirect evidence; the review does not establish long-term disease prevention or a best schedule for an individual.

Understand the context

Evidence type
Systematic review and network meta-analysis of randomized trials
Population or scope
Adults with varied health conditions
Sample or coverage
99 randomized trials; 6,582 participants
Study duration or data period
Varied; most trials were shorter than 24 weeks
Comparison
Alternate-day, whole-day, and time-restricted patterns versus continuous energy restriction or unrestricted eating.

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