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Human trials

What changes when identical meals move later?

Late isocaloric eating increases hunger, decreases energy expenditure, and modifies metabolic pathways in adults with overweight and obesity

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Fasting Free source summary: https://fastingfree.com/education/vujovic-2022-late-eating/

PLAIN-LANGUAGE SUMMARY

What it found

Later meals increased hunger, reduced energy expenditure during waking hours, and altered pathways measured in fat tissue.

Keep these limits in view

A short mechanism study does not establish long-term weight change or a universal time to stop eating. Participants maintained their weight, and the controlled laboratory setting differs from everyday life.

Understand the context

Evidence type
Randomized crossover laboratory trial
Population or scope
Adults with overweight or obesity without diabetes
Sample or coverage
16 completed both conditions
Study duration or data period
Two short inpatient protocols; meal schedules tested on days 3–6
Comparison
Identical meals served earlier or delayed by 4 hours 10 minutes, with calories, sleep, light, and activity controlled.

Research terms in this source

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