Human trials
The 4:3 trial included intensive behavioral support
The Effect of 4:3 Intermittent Fasting on Weight Loss at 12 Months: A Randomized Clinical Trial
Published
View source reference
This reference credits the original source. The plain-language summary on this page is by Fasting Free.
Saved only in this browser, after you choose Save.
Fasting Free source summary: https://fastingfree.com/education/catenacci-2025-drift/
PLAIN-LANGUAGE SUMMARY
What it found
The 4:3 group lost about 2.9 kg more than the daily-restriction group at one year.
Keep these limits in view
These were reduced-energy days, not three days without food. Incomplete follow-up and intensive support limit generalization to unsupervised fasting or daily eating windows.
Understand the context
- Evidence type
- Randomized controlled trial
- Population or scope
- Adults with overweight or obesity
- Sample or coverage
- 165 randomized; 125 completed
- Study duration or data period
- 12 months
- Comparison
- An 80% energy reduction on three nonconsecutive days versus daily restriction; both groups received intensive behavioral and activity support.
Research terms in this source
Open a definition for help reading the study.