Human trials
TEMPUS: eating windows, exercise, and liver fat
Effects of time-restricted eating and supervised exercise on intrahepatic fat and cardiometabolic health in adults with obesity: the TEMPUS randomized controlled trial
Published
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Fasting Free source summary: https://fastingfree.com/education/clavero-2026-tempus/
PLAIN-LANGUAGE SUMMARY
What it found
MRI-measured liver-fat change, the primary outcome, did not clearly differ between the active interventions and usual care, or between active groups.
Keep these limits in view
This short, single-location trial does not settle longer-term liver outcomes. The publisher labels the peer-reviewed article an early version, not a preprint.
Understand the context
- Evidence type
- Randomized controlled trial
- Population or scope
- Adults with obesity in Spain
- Sample or coverage
- 187 randomized
- Study duration or data period
- 12 weeks for the primary outcome
- Comparison
- An 8-hour window, supervised exercise, or both, versus diet and activity education received by all groups.
Research terms in this source
Open a definition for help reading the study.