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Research reviews

Glucose evidence in prediabetes and type 2 diabetes

Effects of time-restricted eating on markers of glucose metabolism and regulation in individuals with prediabetes or type 2 diabetes: a systematic review and meta-analysis of randomised controlled trials

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Fasting Free source summary: https://fastingfree.com/education/viple-2026-glucose-review/

PLAIN-LANGUAGE SUMMARY

What it found

The overall HbA1c estimate was −0.30 percentage points (95% confidence interval: −0.63 to 0.02), which did not establish a clear difference. Fasting glucose was modestly lower.

Keep these limits in view

Small, short studies leave uncertainty. Subgroup findings should not replace the overall estimate or be treated as evidence of diabetes prevention.

Understand the context

Evidence type
Systematic review and meta-analysis of randomized trials
Population or scope
Adults with prediabetes or type 2 diabetes
Sample or coverage
10 randomized trials; 599 participants
Study duration or data period
Average follow-up about 4 months
Comparison
Time-restricted eating versus control conditions without time restriction.

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